Article
[Polymorphism in the N-acetyltransferase 2 gene in patients with lung cancer. Short communication].
Pneumonologia i alergologia polska - 1 Jan 2012
Zabost Anna, Roszkowska-Śliż Barbara, Wiatr Elżbieta, Radzikowska Elżbieta, Rogala Ewa, Zych Jacek, Zwolska Zofia, Augustynowicz-Kopeć Ewa, Roszkowski-Śliż Kazimierz, Szczepulska-Wójcik Ewa
Abstract excerpt
INTRODUCTION: Individual's risk of developing lung cancer depends not only on exposure to tobacco smoke, but also on the activity of enzymes involved in the activation or deactivation of carcinogens. Arylamine N-acetyltransferase (EC 2.3.1.5) is an enzyme involved in biotransformation of xenobiotics, mainly aromatic and heterocyclic amines and hydrazines. The different acetylation phenotypes within a population...
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