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Detection of HPV-DNA, p53 alterations, and methylation in penile squamous cell carcinoma in Japanese men.

Pathology international - 1 Aug 2008

Yanagawa Naoki, Osakabe Mitsumasa, Hayashi Masahiro, Tamura Gen, Motoyama Teiichi

Abstract excerpt

Penile carcinoma is a rare disease, accordingly there are few studies on molecular changes, and these results also vary greatly. A total of 26 penile squamous cell carcinomas in Japanese men were studied with respect to HPV, p53 alterations, and methylation of gene promoter region. HPV-DNA was detected in three of 26 patients (11.5%). Overexpression of p53 was observed in 13 of 26 patients (50%), and p53 gene...

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Identifiers

PMID: 18705766
DOI: 10.1111/j.1440-1827.2008.02259.x

Genes

FHIT
MGMT
RUNX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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