Article
Chronic anterior uveitis following bacille Calmette-Guérin vaccination: molecular mimicry in action?
Journal of pediatric ophthalmology and strabismus - 1 Jan 2000
Spratt Alexander, Key Tim, Vivian Anthony J
Abstract excerpt
A 13-year-old girl developed bilateral chronic anterior uveitis following bacille Calmette-Guérin (BCG) vaccination. HLA testing was negative for B27 but positive for DRB1 *0404, a variant of DR4 often associated with rheumatoid arthritis. The authors propose her HLA repertoire allowed for a BCG-induced abnormal autoimmune response by the mechanism of molecular mimicry.
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