Article

Viral Molecular Mimicry Influences the Antitumor Immune Response in Murine and Human Melanoma

2020-09-10

Abstract excerpt

Molecular mimicry is known to be one of the leading mechanisms by which infectious agents may induce autoimmunity. However, whether a similar mechanism triggers anti-tumor immune response is unexplored, and the role of anti-viral T-cells infiltrating the tumor has remained anecdotal. To address this question, we first developed a bioinformatic tool to identify tumor peptides with high similarity to viral epitopes....

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Literature Corpus work: e8d375ce-2749-56c9-8104-01f48c4f4624
DOI: 10.1101/2020.09.09.20191171

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