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Article

Environmental microbes and uveitis: is microbial exposure always bad?

Scandinavian journal of immunology - 1 Jun 2015

Massilamany C, Gangaplara A, Reddy J

Abstract excerpt

The eye generally is considered to be an immune-privileged organ, but this notion is being increasingly challenged as ocular antigens can be expressed in the generative lymphoid organs, resulting in attainment of self-tolerance. What triggers a break in this tolerant state is a fundamental question in autoimmunity research. The general belief is that exposure to environmental microbes can break self-tolerance in...

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Identifiers

PMID: 25833717
DOI: 10.1111/sji.12297

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