Article
Describing partially unfolded states of proteins from sparse NMR data.
Journal of biomolecular NMR - 1 Nov 2005
Fuentes Gloria, Nederveen Aart J, Kaptein Robert, Boelens Rolf, Bonvin Alexandre M J J
Abstract excerpt
Proteins involved in signal transduction can usually be present in two states: an inactive and an active (signaling) state. In the case of photoreceptors such as PYP, it has been shown that the signaling state has a large degree of structural and dynamic disorder. Conventional structural NMR approaches present difficulties in describing such partially unfolded states. Owing to the disordered dynamical and...
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