Article
IL-10, TGF-beta, IL-2, IL-12, and IFN-gamma cytokine gene polymorphisms in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Nov 2008
Movahedi Masoud, Mahdaviani Seyed Alireza, Rezaei Nima, Moradi Batoul, Dorkhosh Shahin, Amirzargar Ali Akbar
Abstract excerpt
Asthma is a complex respiratory disease, characterized by airway inflammation and reversible airway obstruction. Both genetic and environmental factors are important in the development and expression of the disease. In order to analyze the genetic profile of Th1 and Th2 cytokines in Iranian asthmatic patients, this study was performed. The allele and genotype frequencies of a number of polymorphic genes coding...
Topics
- Asthma
- Cytokines
- Female
- Gene Frequency
- Genotype
- Humans
- Interferon-gamma
- Interleukin-10
- Interleukin-12
- Interleukin-2
- Iran
- Male
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Transforming Growth Factor beta
