Article
Haplotype-tagging interleukin-10 promoter polymorphism is associated with reduced risk of retinal artery occlusion.
Molecular vision - 4 Apr 2007
Weger Martin, Steinbrugger Iris, El-Shabrawi Yosuf, Wegscheider Beate Julia, Weger Wolfgang, Renner Wilfried, Schmut Otto, Haas Anton
Abstract excerpt
PURPOSE: Pro- and anti-inflammatory cytokines, including interleukin 10 (IL-10), play an essential role in atherogenesis. Increased IL-10 production has been found among carriers of the IL10 [TCATA] haplotype, which is formed by five polymorphisms at position -3575, -2763, -1082, -819, and -592 i...
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