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Article

DNA methylation patterns in bladder cancer and washing cell sediments: a perspective for tumor recurrence detection

14 Aug 2008

Abstract excerpt

BACKGROUND: Epigenetic alterations are a hallmark of human cancer. In this study, we aimed to investigate whether aberrant DNA methylation of cancer-associated genes is related to urinary bladder cancer recurrence. METHODS: A set of 4 genes, including CDH1 (E-cadherin), SFN (stratifin), RARB (retinoic acid receptor, beta) and RASSF1A (Ras association (RalGDS/AF-6) domain family 1), had their methylation patterns...

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PMID: 18702824
DOI: 10.1186/1471-2407-8-238

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