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Article

Quantitation of Promoter Methylation of Multiple Genes in Urine DNA and Bladder Cancer Detection

18 Jul 2006

Abstract excerpt

BACKGROUND: The noninvasive identification of bladder tumors may improve disease control and prevent disease progression. Aberrant promoter methylation (i.e., hypermethylation) is a major mechanism for silencing tumor suppressor genes and other cancer-associated genes in many human cancers, including bladder cancer. METHODS: A quantitative fluorogenic real-time polymerase chain reaction (PCR) assay was used to...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 16849682
DOI: 10.1093/jnci/djj265

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