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Comparative Proteomic Analysis of Matched Primary and Metastatic Melanoma Cell Lines

13 Aug 2008

Abstract excerpt

Identification of the biochemical pathways involved in the transformation from primary to metastatic melanoma is an area under intense investigation. A 2DE proteomics approach has been applied herein to the matched patient primary and metastatic melanoma cell lines WM-115 and WM-266-4, respectively, to better understand the processes that underlie tumor progression. Image analysis between samples aligned 470...

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PMID: 18698805
DOI: 10.1021/pr800174k

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