Article

Proteomic analysis of exosomes from lymphatic affluents reveals their implications in developing premetastatic niche in melanoma

2025-05-24

Abstract excerpt

Melanoma is an aggressive form of skin cancer that often spreads via lymphatic pathways to regional and distant sites. Melanoma-derived lymphatic exosomes play a crucial role in forming a tumor-supportive environment for metastasis, or premetastatic niche, within the first tumor draining lymph node, also known as the sentinel lymph node (SLN). Therefore, analyzing the proteomic content of tumor-draining lymphatic...

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Literature Corpus work: d62b8fa7-f5fe-5a8c-8540-c610c8322504
DOI: 10.1101/2025.05.21.655399

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