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Article

Clinical Proteomics of Metastatic Melanoma Reveals Profiles of Organ Specificity and Treatment Resistance.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2021

Beck Lir, Harel Michal, Yu Shun, Markovits Ettai, Boursi Ben, Markel Gal, Geiger Tamar

Abstract excerpt

PURPOSE: Treatment of metastatic melanoma has dramatically improved in recent years, thanks to the development of immunotherapy and BRAF-MEK-targeted therapies. However, these developments revealed marked heterogeneity in patient response, which is yet to be fully understood. In this work, we aimed to associate the proteomic profiles of metastatic melanoma with the patient clinical information, to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 33446566
DOI: 10.1158/1078-0432.CCR-20-3752

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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