Article
Double-faced cell-mediated immunity in beta-thalassemia major: stimulated phenotype versus suppressed activity.
Annals of hematology - 1 Jan 2009
Gharagozloo Marjan, Karimi Mehran, Amirghofran Zahra
Abstract excerpt
In this study, the immunologic abnormalities of Iranian beta-thalassemia major patients were characterized, considering their clinical parameters including splenectomy status and iron overload. Serum samples and peripheral blood mononuclear cells were collected from 28 patients and 30 age- and sex-matched healthy individuals. Patients with thalassemia showed significantly increased absolute lymphocyte counts...
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