Article
Non-transfusion-dependent thalassemias.
Haematologica - 1 Jun 2013
Musallam Khaled M, Rivella Stefano, Vichinsky Elliott, Rachmilewitz Eliezer A
Abstract excerpt
Non-transfusion-dependent thalassemias include a variety of phenotypes that, unlike patients with beta (β)-thalassemia major, do not require regular transfusion therapy for survival. The most commonly investigated forms are β-thalassemia intermedia, hemoglobin E/β-thalassemia, and α-thalassemia intermedia (hemoglobin H disease). However, transfusion-independence in such patients is not without side effects....
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