Article
[Expression and identification of recombinant P-selectin and P-selectin glycoprotein ligand-1].
Sheng li xue bao : [Acta physiologica Sinica] - 25 Aug 2008
Pei Xin-Hui, Lin Zhi-Xin, Geng Jian-Guo
Abstract excerpt
P-selectin, one of the membrane proteins, expresses on platelet and endothelia and interacts with P-selectin glycoprotein ligand-1 (PSGL-1) on leukocyte membrane. This interaction mediates leukocytes rolling on endothelial membrane and then induces leukocyte recruitment to the site of infection or tissue injury. In the present study, we constructed the recombinant wild type human P-selectin, its calcium-binding...
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