Comparative Expression Profiling in Pulmonary Fibrosis Suggests a Role of Hypoxia-inducible Factor-1α in Disease Pathogenesis

doi:10.1164/rccm.200705-683oc

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Article

Comparative Expression Profiling in Pulmonary Fibrosis Suggests a Role of Hypoxia-inducible Factor-1α in Disease Pathogenesis

29 Aug 2007

Abstract excerpt

RATIONALE: Despite intense research efforts, the etiology and pathogenesis of idiopathic pulmonary fibrosis remain poorly understood. OBJECTIVES: To discover novel genes and/or cellular pathways involved in the pathogenesis of the disease. METHODS: We performed expression profiling of disease progression in a well-characterized animal model of the disease. Differentially expressed genes that were identified were...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 17761615
DOI: 10.1164/rccm.200705-683oc

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