Article
Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association.
Molecular biology of the cell - 1 Oct 2008
Perng Ming-Der, Wen Shu-Fang, Gibbon Terry, Middeldorp Jinte, Sluijs Jacqueline, Hol Elly M, Quinlan Roy A
Abstract excerpt
The glial fibrillary acidic protein (GFAP) gene is alternatively spliced to give GFAP-alpha, the most abundant isoform, and seven other differentially expressed transcripts including GFAP-delta. GFAP-delta has an altered C-terminal domain that renders it incapable of self-assembly in vitro. When...
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