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Article

Function of neuromuscular synapses in the zebrafish choline-acetyltransferase mutant bajan.

Journal of neurophysiology - 1 Oct 2008

Wang Meng, Wen Hua, Brehm Paul

Abstract excerpt

We have identified a zebrafish mutant line, bajan, in which compromised motility and fatigue result from a point mutation in the gene coding choline acetyltransferase (ChAT), the enzyme responsible for acetylcholine (ACh) synthesis. Although the mutation predicts loss of ChAT function, bajan inexplicably retains low levels of neuromuscular transmission. We exploited this residual activity and determined the...

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Identifiers

PMID: 18684905
DOI: 10.1152/jn.90517.2008
PMCID: PMC2576202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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