Article
Prognostic value of mitochondrial DNA4977 deletion and mitochondrial DNA copy number in patients with stable coronary artery disease.
Atherosclerosis - 1 Sept 2018
Vecoli Cecilia, Borghini Andrea, Pulignani Silvia, Mercuri Antonella, Turchi Stefano, Carpeggiani Clara, Picano Eugenio, Andreassi Maria Grazia
Abstract excerpt
BACKGROUND AND AIMS: Mitochondrial DNA copy number (mtDNA-CN) depletion has been recently associated with an increased cardiovascular risk. However, the integrity of mtDNA is another key aspect of the energy metabolism and mitochondrial function. We investigated the prognostic role of peripheral blood common mitochondrial deletion (mtDNA4977) and mtDNA-CN on long-term major adverse cardiac events (MACEs) and...
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