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In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation

20 Mar 2024

Abstract excerpt

Direct exposure to the fungal species Alternaria alternata is a major risk factor for the development of asthma, allergic rhinitis, and inflammation. As of November 23rd 2020, the NCBI protein database showed 11,227 proteins from A. alternata genome as hypothetical proteins (HPs). Allergens are the main causative of several life-threatening diseases, especially in fungal infections. Therefore, the main aim of the...

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PMID: 38509156
DOI: 10.1038/s41598-024-55463-1

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