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Article

Histological profile of tumours from <i>MYCN</i> transgenic mice

4 Aug 2008

Abstract excerpt

BACKGROUND: MYCN is the most commonly amplified gene in human neuroblastomas. This proto-oncogene has been overexpressed in a mouse model of the disease in order to explore the role of MYCN in this tumour. AIMS: To report the histopathological features of neuroblastomas from MYCN transgenic mice. METHODS: 27 neuroblastomas from hemizygous transgenic mice and four tumours from homozygous mice were examined...

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PMID: 18682419
DOI: 10.1136/jcp.2007.054627

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