Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A gene-expression-based neural code for food abundance that modulates lifespan.

eLife - 12 May 2015

Entchev Eugeni V, Patel Dhaval S, Zhan Mei, Steele Andrew J, Lu Hang, Ch'ng QueeLim

Abstract excerpt

How the nervous system internally represents environmental food availability is poorly understood. Here, we show that quantitative information about food abundance is encoded by combinatorial neuron-specific gene-expression of conserved TGFβ and serotonin pathway components in Caenorhabditis elegans. Crosstalk and auto-regulation between these pathways alters the shape, dynamic range, and population variance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eating

Share to Longevity

Share to Nervous System

Share to Serotonin

Share to Transforming Growth Factor beta

Share to Tryptophan Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 25962853
DOI: 10.7554/eLife.06259
PMCID: PMC4417936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A gene-expression-based neural code for food abundance that modulates lifespan.PMID 25962853Read ↗

Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding.Semantic proximity Read ↗

Genetic variants that modify neuroendocrine gene expression and foraging behavior of C. elegans.Semantic proximity Read ↗

Molecular and sensory basis of a food related two-state behavior in C. elegans.Semantic proximity Read ↗

Manipulation of components that control feeding behavior in Drosophila melanogaster increases sensitivity to amino acid starvation.Semantic proximity Read ↗

FMRFamide-like peptides expand the behavioral repertoire of a densely connected nervous system.Semantic proximity Read ↗

Control of C. elegans larval development by neuronal expression of a TGF-beta homolog.Semantic proximity Read ↗

A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism.Semantic proximity Read ↗

Cell-Autonomous Gβ Signaling Defines Neuron-Specific Steady State Serotonin Synthesis in Caenorhabditis elegans.Semantic proximity Read ↗

Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans.Semantic proximity Read ↗

Gαo and Gαq regulate the expression of daf-7, a TGFβ-like gene, in Caenorhabditis elegans.Semantic proximity Read ↗

Neuronal IL-17 controls <i>C. elegans</i> developmental diapause through CEP-1/p53Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.