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Article

Physiological and transcriptional responses to high concentrations of lactic acid in anaerobic chemostat cultures of Saccharomyces cerevisiae.

Applied and environmental microbiology - 1 Sept 2008

Abbott Derek A, Suir Erwin, van Maris Antonius J A, Pronk Jack T

Abstract excerpt

Based on the high acid tolerance and the simple nutritional requirements of Saccharomyces cerevisiae, engineered strains of this yeast are considered biocatalysts for industrial production of high-purity undissociated lactic acid. However, high concentrations of lactic acid are toxic to S. cerevisiae, thus limiting its growth and product formation. Physiological and transcriptional responses to high...

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PMID: 18676708
DOI: 10.1128/AEM.01030-08
PMCID: PMC2547041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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