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Article

APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages.

Virology - 30 Sept 2008

Miyagi Eri, Schwartzkopff Franziska, Plishka Ronald, Buckler-White Alicia, Clouse Kathleen A, Strebel Klaus

Abstract excerpt

APOBEC3G (APO3G) is a cellular cytidine deaminase with potent antiviral activity. In the case of HIV, the antiviral activity of APO3G is counteracted by the viral Vif protein. Monocyte-derived macrophages (MDM) are terminally differentiated, non-dividing cells susceptible to HIV infection. Human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Share to vif Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 18675436
DOI: 10.1016/j.virol.2008.06.033
PMCID: PMC2614695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18675436-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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