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Article

In vitro modeling of the HIV-macrophage reservoir

21 Aug 2006

Abstract excerpt

Macrophages are recognized as a putative reservoir for HIV-1, but whether HIV can establish latent infection in this cell type is not known. An in vitro model using long-term cultured primary human monocyte-derived macrophages (MDM) infected with an M-tropic, enhanced green fluorescent protein (EGFP) tagged reporter virus was developed to test the hypothesis that HIV can establish a latent infection of this cell...

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PMID: 16923921
DOI: 10.1189/jlb.0206126

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