Article
Pharmacogenetics of intestinal absorption.
Current drug delivery - 1 Jul 2008
Nakamura Tsutomu, Yamamori Motohiro, Sakaeda Toshiyuki
Abstract excerpt
The small intestine is the primary site of absorption for many drugs administered orally and so is the target tissue for pharmacotherapeutic strategies to control the oral absorption of drugs. Drug transporters, including the ATP-binding cassette (ABC) superfamily and the solute carrier (SLC) superfamily, have been considered to play a physiological role in regulating the absorption of xenobiotics, and variations...
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