Article
Prediction of sustained virological response by ribavirin plasma concentration at week 4 of therapy in hepatitis C virus genotype 1 patients.
Antiviral therapy - 1 Jan 2008
Maynard Marianne, Pradat Pierre, Gagnieu Marie-Claude, Souvignet Claude, Trepo Christian
Abstract excerpt
BACKGROUND: Pegylated interferon/ribavirin combination is currently the standard treatment for chronic hepatitis C virus (HCV) infection. Body weight adjustment of ribavirin is crucial for response. However, previous studies found no relation between ingested dose and plasma concentration. The aim of this study was to define the ribavirin trough plasma concentration at week 4 (W4) associated with sustained...
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