Article
Plasma ribavirin trough concentrations during treatment of chronic hepatitis C in genotype-1 patients.
Journal of clinical gastroenterology - 1 Apr 2012
Muñoz-de-Rueda Paloma, Ruiz-Extremera Angeles, Candel Jose M, Quiles Rosa, Martín Ana Belen, Diago Moises, Andrade Raul, Navarro Jose M, Gila Ana, León Josefa, Carazo Angel, Quintero Dolores, Salmerón Javier
Abstract excerpt
GOALS: To investigate the correlation between virological response and plasma ribavirin trough concentrations (RBV Ctrough) during the full period of chronic hepatitis C (CHC) treatment. STUDY: Multicenter prospective cohort study. Total 119 patients with CHC genotype-1 were treated with peginterferon alfa-2a (pegIFN) and RBV for 48 weeks. RBV quantification was carried out at week 4 (W4), W8, W12, W16, W24, W32,...
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