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Article

Parkin-mediated ubiquitination regulates phospholipase C-gamma1.

Journal of cellular and molecular medicine - 1 Sept 2009

Dehvari Nodi, Sandebring Anna, Flores-Morales Amilcar, Mateos Laura, Chuan Yin-Choy, Goldberg Matthew S, Cookson Mark R, Cowburn Richard F, Cedazo-Mínguez Angel

Abstract excerpt

Mutations in parkin cause autosomal recessive forms of Parkinson's disease (PD), with an early age of onset and similar pathological phenotype to the idiopathic disease. Parkin has been identified as an E3 ubiquitin ligase that mediates different types of ubiquitination, which has made the search for substrates an intriguing possibility to identify pathological mechanisms linked to PD. In this study, we present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

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Source

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Identifiers

PMID: 18671761
DOI: 10.1111/j.1582-4934.2008.00443.x
PMCID: PMC2832102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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