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Article

High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies.

PLoS genetics - 1 Aug 2008

Srivatsan Anjana, Han Yi, Peng Jianlan, Tehranchi Ashley K, Gibbs Richard, Wang Jue D, Chen Rui

Abstract excerpt

Whole-genome sequencing is a powerful technique for obtaining the reference sequence information of multiple organisms. Its use can be dramatically expanded to rapidly identify genomic variations, which can be linked with phenotypes to obtain biological insights. We explored these potential applications using the emerging next-generation sequencing platform Solexa Genome Analyzer, and the well-characterized model...

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Identifiers

PMID: 18670626
DOI: 10.1371/journal.pgen.1000139
PMCID: PMC2474695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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