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Article

Basal budding and replication of the murine leukemia virus are independent of the gag L domains.

Journal of virology - 1 Oct 2008

Sabo Yosef, Laham-Karam Nihay, Bacharach Eran

Abstract excerpt

Moloney murine leukemia virus (MMuLV) Gag protein contains three identified late (L) domains, PPPY, YPAL, and PSAP, which are thought to interact with the endosomal sorting machinery to assist budding. We created single and combined L-domain mutants in all permutations and tested the resulting clones for budding and replication. Budding and replication of all viruses with mutated PPPY were greatly reduced;...

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Source

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Identifiers

PMID: 18667521
DOI: 10.1128/JVI.00741-08
PMCID: PMC2546960

Genes

PSAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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