Article
Mutation of YMYL in the Nipah virus matrix protein abrogates budding and alters subcellular localization.
Journal of virology - 1 Dec 2006
Ciancanelli Michael J, Basler Christopher F
Abstract excerpt
Matrix (M) proteins reportedly direct the budding of paramyxoviruses from infected cells. In order to begin to characterize the assembly process for the highly lethal, emerging paramyxovirus Nipah virus (NiV), we have examined the budding of NiV M. We demonstrated that expression of the NiV M protein is sufficient to produce budding virus-like particles (VLPs) that are physically and morphologically similar to...
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