Article
Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum.
The Journal of biological chemistry - 17 Oct 2008
Colomina Neus, Ferrezuelo Francisco, Wang Hongyin, Aldea Martí, Garí Eloi
Abstract excerpt
Whi3 is an RNA-binding protein associated with the endoplasmic reticulum (ER) that binds the CLN3 mRNA and plays a key role in the efficient retention of cyclin Cln3 at the ER. In the present work, we have identified new Whi3-associated mRNAs by a genomic approach. A large and significant number of these Whi3 targets encode for membrane and exocytic proteins involved in processes such as transport and cell wall...
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