Article
A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients.
Cancer letters - 8 Dec 2008
Quaresima Barbara, Crugliano Telma, Gaspari Marco, Faniello Maria Concetta, Cosimo Paola, Valanzano Rosa, Genuardi Maurizio, Cannataro Mario, Veltri Pierangelo, Baudi Francesco, Doldo Patrizia, Cuda Giovanni, Venuta Salvatore, Costanzo Francesco
Abstract excerpt
Familial adenomatous polyposis (FAP) is one of the most important clinical hereditary forms of inherited susceptibility to colorectal cancer and is characterized by a high degree of phenotypic heterogeneity. We used a mass spectrometry driven-proteomic strategy to identify serum molecules differently expressed in FAP patients. The data obtained were subsequently processed by bioinformatic analysis and confirmed...
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