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Immunoscreening of the extracellular proteome of colorectal cancer cells

25 Feb 2010

Abstract excerpt

BACKGROUND: The release of proteins from tumors can trigger an immune response in cancer patients involving T lymphocytes and B lymphocytes, which results in the generation of antibodies to tumor-derived proteins. Many studies aim to use humoral immune responses, namely autoantibody profiles, directly, as clinical biomarkers. Alternatively, the antibody immune response as an amplification system for tumor...

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PMID: 20184735
DOI: 10.1186/1471-2407-10-70

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