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Article

Crystal structure of the covalent intermediate of human cytosolic beta-glucosidase.

Biochemical and biophysical research communications - 26 Sept 2008

Noguchi Junji, Hayashi Yasuhiro, Baba Yuichi, Okino Nozomu, Kimura Makoto, Ito Makoto, Kakuta Yoshimitsu

Abstract excerpt

Human cytosolic beta-glucosidase, also known as klotho-related protein (KLrP, GBA3), is an enzyme that hydrolyzes various beta-D-glucosides, including glucosylceramide. We recently reported the crystal structure of KLrP in complex with glucose [Y. Hayashi, N. Okino, Y. Kakuta, T. Shikanai, M. Tani, H. Narimatsu, M. Ito, Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase, J. Biol. Chem....

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Identifiers

PMID: 18662675
DOI: 10.1016/j.bbrc.2008.07.089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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