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Article

Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.

British journal of clinical pharmacology - 1 Oct 2008

Hawwa Ahmed F, Millership Jeff S, Collier Paul S, Vandenbroeck Koen, McCarthy Anthony, Dempsey Sid, Cairns Carole, Collins John, Rodgers Colin, McElnay James C

Abstract excerpt

AIMS: To examine the allelic variation of three enzymes involved in 6-mercaptopurine/azathioprine (6-MP/AZA) metabolism and evaluate the influence of these polymorphisms on toxicity, haematological parameters and metabolite levels in patients with acute lymphoblastic leukaemia (ALL) or inflammatory bowel disease (IBD). METHODS: Clinical data and blood samples were collected from 19 ALL paediatric patients and 35...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18662289
DOI: 10.1111/j.1365-2125.2008.03248.x
PMCID: PMC2561120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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