Article
Differential gene expression of TRPM1, the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa horse (Equus caballus).
Genetics - 1 Aug 2008
Bellone Rebecca R, Brooks Samantha A, Sandmeyer Lynne, Murphy Barbara A, Forsyth George, Archer Sheila, Bailey Ernest, Grahn Bruce
Abstract excerpt
The appaloosa coat spotting pattern in horses is caused by a single incomplete dominant gene (LP). Homozygosity for LP (LP/LP) is directly associated with congenital stationary night blindness (CSNB) in Appaloosa horses. LP maps to a 6-cM region on ECA1. We investigated the relative expression of two functional candidate genes located in this LP candidate region (TRPM1 and OCA2), as well as three other linked...
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