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Article

Targeted analysis of four breeds narrows equine Multiple Congenital Ocular Anomalies locus to 208 kilobases.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2011

Andersson Lisa S, Lyberg Katarina, Cothran Gus, Ramsey David T, Juras Rytis, Mikko Sofia, Ekesten Björn, Ewart Susan, Lindgren Gabriella

Abstract excerpt

The syndrome Multiple Congenital Ocular Anomalies (MCOA) is the collective name ascribed to heritable congenital eye defects in horses. Individuals homozygous for the disease allele (MCOA phenotype) have a wide range of eye anomalies, while heterozygous horses (Cyst phenotype) predominantly have cysts that originate from the temporal ciliary body, iris, and/or peripheral retina. MCOA syndrome is highly prevalent...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21465164
DOI: 10.1007/s00335-011-9325-7
PMCID: PMC3098992

Genes

IKZF4
SMARCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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