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Article

Redundant contribution of a Transient Receptor Potential cation channel Member 1 exon 11 single nucleotide polymorphism to equine congenital stationary night blindness.

BMC veterinary research - 21 Jun 2016

Scott Michelle L, John Emily E, Bellone Rebecca R, Ching John C H, Loewen Matthew E, Sandmeyer Lynne S, Grahn Bruce H, Forsyth George W

Abstract excerpt

BACKGROUND: Congenital stationary night-blindness (CSNB) is a recessive autosomal defect in low-light vision in Appaloosa and other horse breeds. This condition has been mapped by linkage analysis to a gene coding for the Transient Receptor Potential cation channel Member 1 (TRPM1). TRPM1 is normally expressed in the ON-bipolar cells of the inner nuclear layer of the retina. Down-regulation of TRPM1 expression in...

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Identifiers

PMID: 27329127
DOI: 10.1186/s12917-016-0745-1
PMCID: PMC4915136

Genes

TRPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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