Article
Genetic risk factors for insidious equine recurrent uveitis in Appaloosa horses.
Animal genetics - 1 Jun 2014
Fritz K L, Kaese H J, Valberg S J, Hendrickson J A, Rendahl A K, Bellone R R, Dynes K M, Wagner M L, Lucio M A, Cuomo F M, Brinkmeyer-Langford C L, Skow L C, Mickelson J R, Rutherford M S, McCue M E
Abstract excerpt
Appaloosa horses are predisposed to equine recurrent uveitis (ERU), an immune-mediated disease characterized by recurring inflammation of the uveal tract in the eye, which is the leading cause of blindness in horses. Nine genetic markers from the ECA1 region responsible for the spotted coat color of Appaloosa horses, and 13 microsatellites spanning the equine major histocompatibility complex (ELA) on ECA20, were...
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