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Article

Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain.

The Journal of biological chemistry - 17 Oct 2008

Schar Christine R, Jensen Jan K, Christensen Anni, Blouse Grant E, Andreasen Peter A, Peterson Cynthia B

Abstract excerpt

Vitronectin and plasminogen activator inhibitor-1 (PAI-1) are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. The interactions between the two proteins have been attributed primarily to binding of the somatomedin B (SMB) domain, which comprises the N-terminal 44 residues of vitronectin, to the flexible joint region of PAI-1,...

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Identifiers

PMID: 18658131
DOI: 10.1074/jbc.M804257200
PMCID: PMC2568936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain.PMID 18658131Read ↗

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