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Article

The factor V HR2 haplotype: prevalence and association of the A4070G and A6755G polymorphisms.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2001

Pecheniuk N M, Morris C P, Walsh T P, Marsh N A

Abstract excerpt

Recently, a polymorphism was identified in exon 25 of the factor V gene that is possibly a functional candidate for the HR2 haplotype. This haplotype is characterized by a single base substitution named R2 (A4070G) in the B domain of the protein. A mutation (A6755G; 2194Asp-->Gly) located near the C terminus has been hypothesized to influence protein folding and glycosylation, and might be responsible for the...

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PMID: 11414634
DOI: 10.1097/00001721-200104000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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