Article
The effect of ancient DNA damage on inferences of demographic histories.
Molecular biology and evolution - 1 Oct 2008
Axelsson Erik, Willerslev Eske, Gilbert M Thomas P, Nielsen Rasmus
Abstract excerpt
The field of ancient DNA (aDNA) is casting new light on many evolutionary questions. However, problems associated with the postmortem instability of DNA may complicate the interpretation of aDNA data. For example, in population genetic studies, the inclusion of damaged DNA may inflate estimates of diversity. In this paper, we examine the effect of DNA damage on population genetic estimates of ancestral population...
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