Article
Direct functional assessment of the composite phenotype through multivariate projection strategies.
Genomics - 1 Dec 2008
Conesa Ana, Bro Rasmus, García-García Francisco, Prats José Manuel, Götz Stefan, Kjeldahl Karin, Montaner David, Dopazo Joaquín
Abstract excerpt
We present a novel approach for the analysis of transcriptomics data that integrates functional annotation of gene sets with expression values in a multivariate fashion, and directly assesses the relation of functional features to a multivariate space of response phenotypical variables. Multivariate projection methods are used to obtain new correlated variables for a set of genes that share a given function....
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