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Article

Impact of EGFR gene polymorphisms on anticancer drug cytotoxicity in vitro.

Molecular diagnosis & therapy - 1 Jan 2008

Puyo Stéphane, Le Morvan Valérie, Robert Jacques

Abstract excerpt

BACKGROUND AND OBJECTIVE: The epidermal growth factor receptor (EGFR) plays a major role in cell proliferation of epithelial tissues, and its alterations frequently contribute to oncogenesis. Several common polymorphisms of the EGFR gene have been described, at the level of both coding and regulatory sequences. Some of these polymorphisms are associated with alterations of EGFR expression and/or activity and may...

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Share to Antineoplastic Agents
Share to Cell Line, Tumor
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to ErbB Receptors

Share to EGFR gene

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18652519
DOI: 10.1007/BF03256288

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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