Article
Ghrelin receptor gene polymorphisms and body size in children and adults.
The Journal of clinical endocrinology and metabolism - 1 Oct 2008
Garcia Edwin A, Heude Barbara, Petry Clive J, Gueorguiev Maria, Hassan-Smith Zaki K, Spanou Antigoni, Ring Susan M, Dunger David B, Wareham Nicholas, Sandhu Manjinder S, Ong Ken K, Korbonits Márta
Abstract excerpt
BACKGROUND: The GH secretagogue receptor type 1a gene (GHSR) encodes the cognate receptor of ghrelin, a gut hormone that regulates food intake and pituitary GH secretion. Previous studies in U.S. families and a German population suggested GHSR to be a candidate quantitative locus for association with human obesity and growth. AIM: The aim of the study was to test common genetic variation in GHSR for association...
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