Article
Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity.
Diabetes - 1 Jan 2005
Baessler Andrea, Hasinoff Michael J, Fischer Marcus, Reinhard Wibke, Sonnenberg Gabriele E, Olivier Michael, Erdmann Jeanette, Schunkert Heribert, Doering Angela, Jacob Howard J, Comuzzie Anthony G, Kissebah Ahmed H, Kwitek Anne E
Abstract excerpt
The growth hormone secretagogue receptor (GHSR) (ghrelin receptor) plays an important role in the regulation of food intake and energy homeostasis. The GHSR gene lies on human chromosome 3q26 within a quantitative trait locus strongly linked to multiple phenotypes related to obesity and the metabolic syndrome. Because the biological function and location of the GHSR gene make it an excellent candidate gene, we...
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