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Contribution of BRCA1 and BRCA2 germline mutations to early onset breast cancer: a series from north of Morocco.

BMC cancer - 7 Sept 2020

Bakkach Joaira, Mansouri Mohamed, Derkaoui Touria, Loudiyi Ali, El Fahime ElMostafa, Barakat Amina, Ghailani Nourouti Naima, Martinez De Villarreal Jaime, Cortijo Bringas Carlos, Bennani Mechita Mohcine

Abstract excerpt

BACKGROUND: To date, the contribution of BRCA1/2 mutations in Moroccan early onset breast cancer patients remains unknown. Here we assess these genetic alterations for the first time in a cohort from North of Morocco. METHODS: Thirty-three patients diagnosed with breast cancer at the age of ≤40 years were recruited irrespective of breast and/or ovarian cancer family history. Coding regions and intron-exon...

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Identifiers

PMID: 32894085
DOI: 10.1186/s12885-020-07352-9
PMCID: PMC7487731

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